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Chlorin e6-associated photodynamic therapy enhances abscopal antitumor effects via inhibition of PD-1/PD-L1 immune checkpoint

We hypothesized that photodynamic therapy (PDT) with Chlorin e6 (Ce6) enhances antitumor abscopal effects via inhibition of the programmed cell death-1/programmed death-ligand 1 (PD-1/PD-L1) immune checkpoint. By using syngeneic melanoma and pancreatic tumor mouse models, we studied the Ce6-PDT-indu...

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Detalles Bibliográficos
Autores principales: Gurung, Pallavi, Lim, Junmo, Shrestha, Rajeev, Kim, Yong-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030802/
https://www.ncbi.nlm.nih.gov/pubmed/36944686
http://dx.doi.org/10.1038/s41598-023-30256-0

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