Effects of HAR1 on cognitive function in mice and the regulatory network of HAR1 determined by RNA sequencing and applied bioinformatics analysis

Background: HAR1 is a 118-bp segment that lies in a pair of novel non-coding RNA genes. It shows a dramatic accelerated change with an estimated 18 substitutions in the human lineage since the human–chimpanzee ancestor, compared with the expected 0.27 substitutions based on the slow rate of change i...

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Detalles Bibliográficos
Autores principales: Zhang, Luting, Lin, Shengmou, Huang, Kailing, Chen, Allen, Li, Nan, Shen, Shuhan, Zheng, Zhouxia, Shi, Xiaoshun, Sun, Jimei, Kong, Jingyin, Chen, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030831/
https://www.ncbi.nlm.nih.gov/pubmed/36968607
http://dx.doi.org/10.3389/fgene.2023.947144

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