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High-force catch bonds between the Staphylococcus aureus surface protein SdrE and complement regulator factor H drive immune evasion

The invasive bacterial pathogen Staphylococcus aureus recruits the complement regulatory protein factor H (fH) to its surface to evade the human immune system. Here, we report the identification of an extremely high-force catch bond used by the S. aureus surface protein SdrE to efficiently capture f...

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Detalles Bibliográficos
Autores principales: Paiva, Telmo O., Geoghegan, Joan A., Dufrêne, Yves F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030832/
https://www.ncbi.nlm.nih.gov/pubmed/36944849
http://dx.doi.org/10.1038/s42003-023-04660-1