Genetic analyses of DNA repair pathway associated genes implicate new candidate cancer predisposing genes in ancestrally defined ovarian cancer cases

Not all familial ovarian cancer (OC) cases are explained by pathogenic germline variants in known risk genes. A candidate gene approach involving DNA repair pathway genes was applied to identify rare recurring pathogenic variants in familial OC cases not associated with known OC risk genes from a po...

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Detalles Bibliográficos
Autores principales: Alenezi, Wejdan M., Fierheller, Caitlin T., Serruya, Corinne, Revil, Timothée, Oros, Kathleen K., Subramanian, Deepak N., Bruce, Jeffrey, Spiegelman, Dan, Pugh, Trevor, Campbell, Ian G., Mes-Masson, Anne-Marie, Provencher, Diane, Foulkes, William D., Haffaf, Zaki El, Rouleau, Guy, Bouchard, Luigi, Greenwood, Celia M. T., Ragoussis, Jiannis, Tonin, Patricia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030840/
https://www.ncbi.nlm.nih.gov/pubmed/36969007
http://dx.doi.org/10.3389/fonc.2023.1111191

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