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Lysosomal Ca(2+) as a mediator of palmitate-induced lipotoxicity

While the mechanism of lipotoxicity by palmitic acid (PA), an effector of metabolic stress in vitro and in vivo, has been extensively investigated, molecular details of lipotoxicity are still not fully characterized. Since recent studies reported that PA can exert lysosomal stress in addition to wel...

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Detalles Bibliográficos
Autores principales: Oh, Soo-Jin, Hwang, Yeseong, Hur, Kyu Yeon, Lee, Myung-Shik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030853/
https://www.ncbi.nlm.nih.gov/pubmed/36944629
http://dx.doi.org/10.1038/s41420-023-01379-0

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