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Lysosomal Ca(2+) as a mediator of palmitate-induced lipotoxicity
While the mechanism of lipotoxicity by palmitic acid (PA), an effector of metabolic stress in vitro and in vivo, has been extensively investigated, molecular details of lipotoxicity are still not fully characterized. Since recent studies reported that PA can exert lysosomal stress in addition to wel...
Autores principales: | Oh, Soo-Jin, Hwang, Yeseong, Hur, Kyu Yeon, Lee, Myung-Shik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030853/ https://www.ncbi.nlm.nih.gov/pubmed/36944629 http://dx.doi.org/10.1038/s41420-023-01379-0 |
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