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Boolean modeling of mechanosensitive epithelial to mesenchymal transition and its reversal

The significance of biophysical modulators of the epithelial to mesenchymal transition (EMT) is demonstrated by experiments that document full EMT on stiff, nano-patterned substrates in the absence of biochemical induction. Yet, current models focus on biochemical triggers of EMT without addressing...

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Detalles Bibliográficos
Autores principales: Sullivan, Emmalee, Harris, Marlayna, Bhatnagar, Arnav, Guberman, Eric, Zonfa, Ian, Ravasz Regan, Erzsébet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030917/
https://www.ncbi.nlm.nih.gov/pubmed/36968076
http://dx.doi.org/10.1016/j.isci.2023.106321