Cargando…
Boolean modeling of mechanosensitive epithelial to mesenchymal transition and its reversal
The significance of biophysical modulators of the epithelial to mesenchymal transition (EMT) is demonstrated by experiments that document full EMT on stiff, nano-patterned substrates in the absence of biochemical induction. Yet, current models focus on biochemical triggers of EMT without addressing...
Autores principales: | Sullivan, Emmalee, Harris, Marlayna, Bhatnagar, Arnav, Guberman, Eric, Zonfa, Ian, Ravasz Regan, Erzsébet |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030917/ https://www.ncbi.nlm.nih.gov/pubmed/36968076 http://dx.doi.org/10.1016/j.isci.2023.106321 |
Ejemplares similares
-
Boolean model of anchorage dependence and contact inhibition points to coordinated inhibition but semi-independent induction of proliferation and migration
por: Guberman, Eric, et al.
Publicado: (2020) -
Boolean model of growth signaling, cell cycle and apoptosis predicts the molecular mechanism of aberrant cell cycle progression driven by hyperactive PI3K
por: Sizek, Herbert, et al.
Publicado: (2019) -
Translocating proteins compartment-specifically alter the fate of epithelial-mesenchymal transition in a compartmentalized Boolean network model
por: Mendik, Péter, et al.
Publicado: (2022) -
Principles of dynamical modularity in biological regulatory networks
por: Deritei, Dávid, et al.
Publicado: (2016) -
Time to Decide? Dynamical Analysis Predicts Partial Tip/Stalk Patterning States Arise during Angiogenesis
por: Venkatraman, Lakshmi, et al.
Publicado: (2016)