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Evidence of polygenic regulation of the physiological presence of neurofilament light chain in human serum

INTRODUCTION: The measurement of neurofilament light chain (NfL) in blood is a promising biomarker of neurological injury and disease. We investigated the genetic factors that underlie serum NfL levels (sNfL) of individuals without neurological conditions. METHODS: We performed a discovery genome-wi...

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Detalles Bibliográficos
Autores principales: Herrera-Rivero, Marisol, Hofer, Edith, Maceski, Aleksandra, Leppert, David, Benkert, Pascal, Kuhle, Jens, Schmidt, Reinhold, Khalil, Michael, Wiendl, Heinz, Stoll, Monika, Berger, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030935/
https://www.ncbi.nlm.nih.gov/pubmed/36970523
http://dx.doi.org/10.3389/fneur.2023.1145737