Synaptic scaling of corticostriatal circuits underlies hyperactivity in GABA Transporter-1 deficient mice

Homeostatic synaptic scaling entails adjustment of synaptic strength on a cell to prolonged changes of neuronal activity, which is postulated to participate in neuropsychiatric disorders in vivo. Here, we find that sustained elevation in ambient GABA levels, by either genetic deletion or pharmacolog...

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Detalles Bibliográficos
Autores principales: Wu, Yan-Jiao, Yi, Xin, Gu, Xue, Wang, Qi, Jiang, Qin, Li, Ying, Zhu, Michael X., Ding, Jianqing, Li, Wei-Guang, Xu, Tian-Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031039/
https://www.ncbi.nlm.nih.gov/pubmed/36968092
http://dx.doi.org/10.1016/j.isci.2023.106322

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