Palmitoylation controls the stability of 190 kDa ankyrin-G in dendritic spines and is regulated by ZDHHC8 and lithium

INTRODUCTION: AnkG, encoded by the ANK3 gene, is a multifunctional scaffold protein with complex isoform expression: the 480 and 270 kDa isoforms have roles at the axon initial segment and node of Ranvier, whereas the 190 kDa isoform (AnkG-190) has an emerging role in the dendritic shaft and spine h...

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Detalles Bibliográficos
Autores principales: Piguel, Nicolas H., Sanders, Shaun S., De Simone, Francesca I., Martin-de-Saavedra, Maria D., McCoig, Emmarose, Dionisio, Leonardo E., Smith, Katharine R., Thomas, Gareth M., Penzes, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031057/
https://www.ncbi.nlm.nih.gov/pubmed/36969554
http://dx.doi.org/10.3389/fnmol.2023.1144066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031057/
https://www.ncbi.nlm.nih.gov/pubmed/36969554
http://dx.doi.org/10.3389/fnmol.2023.1144066

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