PTEN‐AKT pathway attenuates apoptosis and adverse remodeling in ponatinib‐induced skeletal muscle toxicity following BMP‐7 treatment

Tyrosine kinase inhibitors (TKIs) including ponatinib are commonly used to treat cancer patients. Unfortunately, TKIs induce cardiac as well as skeletal muscle dysfunction as a side effect. Therefore, detailed mechanistic studies are required to understand its pathogenesis and to develop a therapeut...

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Detalles Bibliográficos
Autores principales: Srivastava, Ayushi, Singla, Dinender K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031244/
https://www.ncbi.nlm.nih.gov/pubmed/36945866
http://dx.doi.org/10.14814/phy2.15629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031244/
https://www.ncbi.nlm.nih.gov/pubmed/36945866
http://dx.doi.org/10.14814/phy2.15629

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