G protein-coupled receptor 35 attenuates nonalcoholic steatohepatitis by reprogramming cholesterol homeostasis in hepatocytes

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. Fat accumulation “sensitizes” the liver to insult and leads to nonalcoholic steatohepatitis (NASH). G protein-coupled receptor 35 (GPR35) is involved in metabolic stresses, but its role in NAFLD is unknown....

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Detalles Bibliográficos
Autores principales: Wei, Xiaoli, Yin, Fan, Wu, Miaomiao, Xie, Qianqian, Zhao, Xueqin, Zhu, Cheng, Xie, Ruiqian, Chen, Chongqing, Liu, Menghua, Wang, Xueying, Ren, Ruixue, Kang, Guijie, Zhu, Chenwen, Cong, Jingjing, Wang, Hua, Wang, Xuefu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031266/
https://www.ncbi.nlm.nih.gov/pubmed/36970193
http://dx.doi.org/10.1016/j.apsb.2022.10.011

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