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The isochromosome 20q abnormality of pluripotent cells interrupts germ layer differentiation

Chromosome 20 abnormalities are some of the most frequent genomic changes acquired by human pluripotent stem cell (hPSC) cultures worldwide. Yet their effects on differentiation remain largely unexplored. We investigated a recurrent abnormality also found on amniocentesis, the isochromosome 20q (iso...

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Detalles Bibliográficos
Autores principales:	Vitillo, Loriana, Anjum, Fabiha, Hewitt, Zoe, Stavish, Dylan, Laing, Owen, Baker, Duncan, Barbaric, Ivana, Coffey, Pete
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031278/ https://www.ncbi.nlm.nih.gov/pubmed/36801002 http://dx.doi.org/10.1016/j.stemcr.2023.01.007

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