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The deubiquitinating enzyme 13 retards non-alcoholic steatohepatitis via blocking inactive rhomboid protein 2-dependent pathway

Nowadays potential preclinical drugs for the treatment of nonalcoholic steatohepatitis (NASH) have failed to achieve expected therapeutic efficacy because the pathogenic mechanisms are underestimated. Inactive rhomboid protein 2 (IRHOM2), a promising target for treatment of inflammation-related dise...

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Detalles Bibliográficos
Autores principales: Xu, Minxuan, Tan, Jun, Zhu, Liancai, Ge, Chenxu, Dong, Wei, Dai, Xianling, Kuang, Qin, Zhong, Shaoyu, Lai, Lili, Yi, Chao, Li, Qiang, Lou, Deshuai, Hu, Linfeng, Liu, Xi, Kuang, Gang, Luo, Jing, Feng, Jing, Wang, Bochu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031279/
https://www.ncbi.nlm.nih.gov/pubmed/36970206
http://dx.doi.org/10.1016/j.apsb.2022.12.006