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Managing Different Spectrums of Tuberous Sclerosis Facial Angiofibroma: A Report of Two Cases

Tuberous sclerosis is one of the rarest genetically linked disorders that can affect a multitude of body systems in various forms. Patients with facial angiofibroma may face issues arising from the various modalities and approaches that can be applied. Moreover, surgeons also face challenges in prep...

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Autores principales: Mustaqim, Khairul, Mohd Ghazi, Ahmad Faiz Najmuddin, Harun Nor Rashid, Shawaltul Akhma, Mohamad, Syafiq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031289/
https://www.ncbi.nlm.nih.gov/pubmed/36960246
http://dx.doi.org/10.7759/cureus.35200
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author Mustaqim, Khairul
Mohd Ghazi, Ahmad Faiz Najmuddin
Harun Nor Rashid, Shawaltul Akhma
Mohamad, Syafiq
author_facet Mustaqim, Khairul
Mohd Ghazi, Ahmad Faiz Najmuddin
Harun Nor Rashid, Shawaltul Akhma
Mohamad, Syafiq
author_sort Mustaqim, Khairul
collection PubMed
description Tuberous sclerosis is one of the rarest genetically linked disorders that can affect a multitude of body systems in various forms. Patients with facial angiofibroma may face issues arising from the various modalities and approaches that can be applied. Moreover, surgeons also face challenges in preparing patients for specific interventions. Here, we are reporting the two spectrums of this condition that may present, along with how we managed patients in our center. The first case is a severe form of tuberous sclerosis involving the skin as well as neurological manifestation, while the second case is a milder form. Both were treated with serial excision and electrosurgery, respectively. Facial angiofibroma in tuberous sclerosis can present in various spectrums. Serial excision and electrosurgery are deemed acceptable. Few advancements have been made in the management of this condition, and combination therapies have shown favorable outcomes. Optimizing patient comorbidities is imperative before intervention and multidisciplinary team involvement would ensure patient safety.
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spelling pubmed-100312892023-03-22 Managing Different Spectrums of Tuberous Sclerosis Facial Angiofibroma: A Report of Two Cases Mustaqim, Khairul Mohd Ghazi, Ahmad Faiz Najmuddin Harun Nor Rashid, Shawaltul Akhma Mohamad, Syafiq Cureus Dermatology Tuberous sclerosis is one of the rarest genetically linked disorders that can affect a multitude of body systems in various forms. Patients with facial angiofibroma may face issues arising from the various modalities and approaches that can be applied. Moreover, surgeons also face challenges in preparing patients for specific interventions. Here, we are reporting the two spectrums of this condition that may present, along with how we managed patients in our center. The first case is a severe form of tuberous sclerosis involving the skin as well as neurological manifestation, while the second case is a milder form. Both were treated with serial excision and electrosurgery, respectively. Facial angiofibroma in tuberous sclerosis can present in various spectrums. Serial excision and electrosurgery are deemed acceptable. Few advancements have been made in the management of this condition, and combination therapies have shown favorable outcomes. Optimizing patient comorbidities is imperative before intervention and multidisciplinary team involvement would ensure patient safety. Cureus 2023-02-19 /pmc/articles/PMC10031289/ /pubmed/36960246 http://dx.doi.org/10.7759/cureus.35200 Text en Copyright © 2023, Mustaqim et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Mustaqim, Khairul
Mohd Ghazi, Ahmad Faiz Najmuddin
Harun Nor Rashid, Shawaltul Akhma
Mohamad, Syafiq
Managing Different Spectrums of Tuberous Sclerosis Facial Angiofibroma: A Report of Two Cases
title Managing Different Spectrums of Tuberous Sclerosis Facial Angiofibroma: A Report of Two Cases
title_full Managing Different Spectrums of Tuberous Sclerosis Facial Angiofibroma: A Report of Two Cases
title_fullStr Managing Different Spectrums of Tuberous Sclerosis Facial Angiofibroma: A Report of Two Cases
title_full_unstemmed Managing Different Spectrums of Tuberous Sclerosis Facial Angiofibroma: A Report of Two Cases
title_short Managing Different Spectrums of Tuberous Sclerosis Facial Angiofibroma: A Report of Two Cases
title_sort managing different spectrums of tuberous sclerosis facial angiofibroma: a report of two cases
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031289/
https://www.ncbi.nlm.nih.gov/pubmed/36960246
http://dx.doi.org/10.7759/cureus.35200
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