Prolonged generation of multi-lineage blood cells in wild-type animals from pluripotent stem cells

Regenerating prolonged multi-lineage hematopoiesis from pluripotent stem cells (PSCs), an unlimited cell source, is a crucial aim of regenerative hematology. In this study, we used a gene-edited PSC line and revealed that simultaneous expression of three transcription factors, Runx1, Hoxa9, and Hoxa...

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Detalles Bibliográficos
Autores principales: Peng, Huan, Lin, Yunqing, Hu, Fangxiao, Lv, Cui, Wu, Bingyan, Weng, Qitong, Liu, Lijuan, Xia, Chengxiang, Liu, Xiaofei, Zhao, Yalan, Zhang, Qi, Geng, Yang, Zhang, Mengyun, Wang, Jinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031304/
https://www.ncbi.nlm.nih.gov/pubmed/36801005
http://dx.doi.org/10.1016/j.stemcr.2023.01.009

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