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Analgesia and sedation for intratracheal intubation in the neonatal period: an integrative literature review

OBJECTIVE: to assess evidence available in the literature about the use of sedation and analgesia for intratracheal intubation of newborns. DATA SOURCES: by means of an integrative literature review, the authors looked for evidence related to the theme from the last ten years, indexed in the Pubmed,...

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Autores principales: Naujorks, Silvia, Knob, Gabriele H., Dotto, Patrícia P., Henn, Roseli, Zamberlan, Cláudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031350/
https://www.ncbi.nlm.nih.gov/pubmed/36375493
http://dx.doi.org/10.1016/j.jped.2022.10.003
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author Naujorks, Silvia
Knob, Gabriele H.
Dotto, Patrícia P.
Henn, Roseli
Zamberlan, Cláudia
author_facet Naujorks, Silvia
Knob, Gabriele H.
Dotto, Patrícia P.
Henn, Roseli
Zamberlan, Cláudia
author_sort Naujorks, Silvia
collection PubMed
description OBJECTIVE: to assess evidence available in the literature about the use of sedation and analgesia for intratracheal intubation of newborns. DATA SOURCES: by means of an integrative literature review, the authors looked for evidence related to the theme from the last ten years, indexed in the Pubmed, Medline, Lilacs, Scielo, and Scopus databases, by combining the descriptors: newborn, intratracheal intubation, and analgesia. Articles in Portuguese, English, and Spanish that met the research purpose were included. DATA SUMMARY: After applying the eligibility criteria, ten articles on the topic were obtained, predominantly narrative reviews, retrospective studies, observational studies, and only one non-randomized clinical trial, which characterizes the literature related to the topic as having a low level of scientific evidence. There is still no consensus in the literature on which medications and indications are for use in non-elective intubations, despite the ethical recommendation. DISCUSSION: pain and its deleterious effects should not be neglected. Neonatal Intensive Care Units should have their own protocols regarding sedation and analgesia for intubation considering the individual characteristics of each patient. There is an ethical recommendation regarding the use of sedation and analgesia for intubation since it is a known painful procedure.
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spelling pubmed-100313502023-03-23 Analgesia and sedation for intratracheal intubation in the neonatal period: an integrative literature review Naujorks, Silvia Knob, Gabriele H. Dotto, Patrícia P. Henn, Roseli Zamberlan, Cláudia J Pediatr (Rio J) Review Article OBJECTIVE: to assess evidence available in the literature about the use of sedation and analgesia for intratracheal intubation of newborns. DATA SOURCES: by means of an integrative literature review, the authors looked for evidence related to the theme from the last ten years, indexed in the Pubmed, Medline, Lilacs, Scielo, and Scopus databases, by combining the descriptors: newborn, intratracheal intubation, and analgesia. Articles in Portuguese, English, and Spanish that met the research purpose were included. DATA SUMMARY: After applying the eligibility criteria, ten articles on the topic were obtained, predominantly narrative reviews, retrospective studies, observational studies, and only one non-randomized clinical trial, which characterizes the literature related to the topic as having a low level of scientific evidence. There is still no consensus in the literature on which medications and indications are for use in non-elective intubations, despite the ethical recommendation. DISCUSSION: pain and its deleterious effects should not be neglected. Neonatal Intensive Care Units should have their own protocols regarding sedation and analgesia for intubation considering the individual characteristics of each patient. There is an ethical recommendation regarding the use of sedation and analgesia for intubation since it is a known painful procedure. Elsevier 2022-11-11 /pmc/articles/PMC10031350/ /pubmed/36375493 http://dx.doi.org/10.1016/j.jped.2022.10.003 Text en © 2022 Published by Elsevier Editora Ltda. on behalf of Sociedade Brasileira de Pediatria. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Naujorks, Silvia
Knob, Gabriele H.
Dotto, Patrícia P.
Henn, Roseli
Zamberlan, Cláudia
Analgesia and sedation for intratracheal intubation in the neonatal period: an integrative literature review
title Analgesia and sedation for intratracheal intubation in the neonatal period: an integrative literature review
title_full Analgesia and sedation for intratracheal intubation in the neonatal period: an integrative literature review
title_fullStr Analgesia and sedation for intratracheal intubation in the neonatal period: an integrative literature review
title_full_unstemmed Analgesia and sedation for intratracheal intubation in the neonatal period: an integrative literature review
title_short Analgesia and sedation for intratracheal intubation in the neonatal period: an integrative literature review
title_sort analgesia and sedation for intratracheal intubation in the neonatal period: an integrative literature review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031350/
https://www.ncbi.nlm.nih.gov/pubmed/36375493
http://dx.doi.org/10.1016/j.jped.2022.10.003
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