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Genome-wide methylation analysis of circulating tumor DNA: A new biomarker for recurrent glioblastom

BACKGROUND: Glioblastoma (GBM) is a malignant tumor with a short survival and poor prognosis and a lack of clinically validated biomarkers for diagnosis and prognosis. METHODS: We collected cerebrospinal fluid (CSF) samples and normal CSF sample from recurrent GBM patients and paired tissue samples....

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Detalles Bibliográficos
Autores principales: Dai, Lin, Liu, Zhihui, Zhu, Yi, Ma, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031355/
https://www.ncbi.nlm.nih.gov/pubmed/36967887
http://dx.doi.org/10.1016/j.heliyon.2023.e14339