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An mRNA vaccine elicits STING-dependent antitumor immune responses

Lipid-formulated RNA vaccines have been widely used for disease prevention and treatment, yet their mechanism of action and individual components contributing to such actions remain to be delineated. Here, we show that a therapeutic cancer vaccine composed of a protamine/mRNA core and a lipid shell...

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Detalles Bibliográficos
Autores principales: Chen, Zhe, Meng, Chaoyang, Mai, Junhua, Liu, Yongbin, Li, Hangwen, Shen, Haifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031366/
https://www.ncbi.nlm.nih.gov/pubmed/36970194
http://dx.doi.org/10.1016/j.apsb.2022.11.013

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