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DAPL1 deficiency in mice impairs antioxidant defenses in the RPE and leads to retinal degeneration with AMD-like features

The decreased antioxidant capacity in the retinal pigment epithelium (RPE) is the hallmark of retinal degenerative diseases including age-related macular degeneration (AMD). Nevertheless, the exact regulatory mechanisms underlying the pathogenesis of retinal degenerations remain largely unknown. Her...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoyin, Chen, Huaicheng, Jian, Shuhui, He, Junhao, Liu, Youjia, Han, Shuxian, Chang, Lifu, Li, Pingping, Chen, Ying-ao, Liu, Xiaoyan, Hu, Xiaojuan, Chen, Yu, Hou, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031543/
https://www.ncbi.nlm.nih.gov/pubmed/36933392
http://dx.doi.org/10.1016/j.redox.2023.102675