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DAPL1 deficiency in mice impairs antioxidant defenses in the RPE and leads to retinal degeneration with AMD-like features
The decreased antioxidant capacity in the retinal pigment epithelium (RPE) is the hallmark of retinal degenerative diseases including age-related macular degeneration (AMD). Nevertheless, the exact regulatory mechanisms underlying the pathogenesis of retinal degenerations remain largely unknown. Her...
Autores principales: | Ma, Xiaoyin, Chen, Huaicheng, Jian, Shuhui, He, Junhao, Liu, Youjia, Han, Shuxian, Chang, Lifu, Li, Pingping, Chen, Ying-ao, Liu, Xiaoyan, Hu, Xiaojuan, Chen, Yu, Hou, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031543/ https://www.ncbi.nlm.nih.gov/pubmed/36933392 http://dx.doi.org/10.1016/j.redox.2023.102675 |
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