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Inhibition of human APE1 and MTH1 DNA repair proteins by dextran-coated γ-Fe(2)O(3) ultrasmall superparamagnetic iron oxide nanoparticles

AIM: To quantitatively evaluate the inhibition of human DNA repair proteins APE1 and MTH1 by dextran-coated γ-Fe(2)O(3) ultrasmall superparamagnetic iron oxide nanoparticles (dUSPIONs). Materials & methods: Liquid chromatography–tandem mass spectrometry with isotope-dilution was used to measure...

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Detalles Bibliográficos
Autores principales: Coskun, Erdem, Singh, Neenu, Scanlan, Leona D, Jaruga, Pawel, Doak, Shareen H, Dizdaroglu, Miral, Nelson, Bryant C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031551/
https://www.ncbi.nlm.nih.gov/pubmed/36853189
http://dx.doi.org/10.2217/nnm-2022-0204