Cargando…

Race‐related population attributable fraction of preventable risk factors of dementia: A Latino population‐based study

BACKGROUND: Risk factors for dementia have distinct frequency and impact in relation to race. Our aim was to identify differences in modifiable risk factors of dementia related to races and estimate their population attributable fraction (PAF). METHODS: An epidemiological cohort was used to estimate...

Descripción completa

Detalles Bibliográficos
Autores principales: Borelli, Wyllians Vendramini, Formoso, Carolina Rodrigues, Bieger, Andrei, Ferreira, Pamela Lukasewicz, Zimmer, Eduardo R., Pascoal, Tharick Ali, Chaves, Marcia Lorena Fagundes, Castilhos, Raphael Machado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031750/
https://www.ncbi.nlm.nih.gov/pubmed/36968620
http://dx.doi.org/10.1002/dad2.12408
_version_ 1784910670675836928
author Borelli, Wyllians Vendramini
Formoso, Carolina Rodrigues
Bieger, Andrei
Ferreira, Pamela Lukasewicz
Zimmer, Eduardo R.
Pascoal, Tharick Ali
Chaves, Marcia Lorena Fagundes
Castilhos, Raphael Machado
author_facet Borelli, Wyllians Vendramini
Formoso, Carolina Rodrigues
Bieger, Andrei
Ferreira, Pamela Lukasewicz
Zimmer, Eduardo R.
Pascoal, Tharick Ali
Chaves, Marcia Lorena Fagundes
Castilhos, Raphael Machado
author_sort Borelli, Wyllians Vendramini
collection PubMed
description BACKGROUND: Risk factors for dementia have distinct frequency and impact in relation to race. Our aim was to identify differences in modifiable risk factors of dementia related to races and estimate their population attributable fraction (PAF). METHODS: An epidemiological cohort was used to estimate the prevalence of 10 modifiable risk factors for dementia among five races—White, Black, Brown, Asian, and Indigenous. Sample weighting was used to estimate the prevalence and PAF of each risk factor in each race. RESULTS: A total of 9070 individuals were included. Overall adjusted PAF was the lowest in Indigenous (38.9%), and Asian individuals (41.2%). Race‐related prevalence of individual risk factors was widely variable in our population, but hearing loss was the most important contributor to the overall PAF in all races. CONCLUSIONS: Public policies aiming to reduce preventable risk factors for dementia should take into consideration the race of the target populations. HIGHLIGHTS: Preventable risk factors for dementia vary according to race. Hearing loss presented the highest prevalence among all races studied. Indigenous and Asian individuals presented the lowest population attributable fractions. Black and Brown individuals were more vulnerable to social determinants.
format Online
Article
Text
id pubmed-10031750
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-100317502023-03-23 Race‐related population attributable fraction of preventable risk factors of dementia: A Latino population‐based study Borelli, Wyllians Vendramini Formoso, Carolina Rodrigues Bieger, Andrei Ferreira, Pamela Lukasewicz Zimmer, Eduardo R. Pascoal, Tharick Ali Chaves, Marcia Lorena Fagundes Castilhos, Raphael Machado Alzheimers Dement (Amst) Research Articles BACKGROUND: Risk factors for dementia have distinct frequency and impact in relation to race. Our aim was to identify differences in modifiable risk factors of dementia related to races and estimate their population attributable fraction (PAF). METHODS: An epidemiological cohort was used to estimate the prevalence of 10 modifiable risk factors for dementia among five races—White, Black, Brown, Asian, and Indigenous. Sample weighting was used to estimate the prevalence and PAF of each risk factor in each race. RESULTS: A total of 9070 individuals were included. Overall adjusted PAF was the lowest in Indigenous (38.9%), and Asian individuals (41.2%). Race‐related prevalence of individual risk factors was widely variable in our population, but hearing loss was the most important contributor to the overall PAF in all races. CONCLUSIONS: Public policies aiming to reduce preventable risk factors for dementia should take into consideration the race of the target populations. HIGHLIGHTS: Preventable risk factors for dementia vary according to race. Hearing loss presented the highest prevalence among all races studied. Indigenous and Asian individuals presented the lowest population attributable fractions. Black and Brown individuals were more vulnerable to social determinants. John Wiley and Sons Inc. 2023-03-22 /pmc/articles/PMC10031750/ /pubmed/36968620 http://dx.doi.org/10.1002/dad2.12408 Text en © 2023 The Authors. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals, LLC on behalf of Alzheimer's Association. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Articles
Borelli, Wyllians Vendramini
Formoso, Carolina Rodrigues
Bieger, Andrei
Ferreira, Pamela Lukasewicz
Zimmer, Eduardo R.
Pascoal, Tharick Ali
Chaves, Marcia Lorena Fagundes
Castilhos, Raphael Machado
Race‐related population attributable fraction of preventable risk factors of dementia: A Latino population‐based study
title Race‐related population attributable fraction of preventable risk factors of dementia: A Latino population‐based study
title_full Race‐related population attributable fraction of preventable risk factors of dementia: A Latino population‐based study
title_fullStr Race‐related population attributable fraction of preventable risk factors of dementia: A Latino population‐based study
title_full_unstemmed Race‐related population attributable fraction of preventable risk factors of dementia: A Latino population‐based study
title_short Race‐related population attributable fraction of preventable risk factors of dementia: A Latino population‐based study
title_sort race‐related population attributable fraction of preventable risk factors of dementia: a latino population‐based study
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031750/
https://www.ncbi.nlm.nih.gov/pubmed/36968620
http://dx.doi.org/10.1002/dad2.12408
work_keys_str_mv AT borelliwylliansvendramini racerelatedpopulationattributablefractionofpreventableriskfactorsofdementiaalatinopopulationbasedstudy
AT formosocarolinarodrigues racerelatedpopulationattributablefractionofpreventableriskfactorsofdementiaalatinopopulationbasedstudy
AT biegerandrei racerelatedpopulationattributablefractionofpreventableriskfactorsofdementiaalatinopopulationbasedstudy
AT ferreirapamelalukasewicz racerelatedpopulationattributablefractionofpreventableriskfactorsofdementiaalatinopopulationbasedstudy
AT zimmereduardor racerelatedpopulationattributablefractionofpreventableriskfactorsofdementiaalatinopopulationbasedstudy
AT pascoaltharickali racerelatedpopulationattributablefractionofpreventableriskfactorsofdementiaalatinopopulationbasedstudy
AT chavesmarcialorenafagundes racerelatedpopulationattributablefractionofpreventableriskfactorsofdementiaalatinopopulationbasedstudy
AT castilhosraphaelmachado racerelatedpopulationattributablefractionofpreventableriskfactorsofdementiaalatinopopulationbasedstudy