Single-cell transcriptomic analysis of normal and pathological tissues from the same patient uncovers colon cancer progression

The aim of the present study was to elucidate the evolutionary trajectory of colon cells from normal colon mucosa, to adenoma, then to carcinoma in the same microenvironment. Normal colon, adenoma and carcinoma tissues from the same patient were analyzed by single-cell sequencing, which perfectly si...

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Detalles Bibliográficos
Autores principales: Sun, Ruifang, Yang, Yang, Lü, Weidong, Yang, Yanqi, Li, Yulong, Liu, Zhigang, Diao, Dongmei, Wang, Yang, Chang, Su’e, Lu, Mengnan, Jiang, Qiuyu, Dai, Bingling, Ma, Xiaobin, Zhao, Chang’an, Lü, Moqi, Zhang, Juan, Ding, Caixia, Li, Na, Zhang, Jian, Xiao, Zhengtao, Zhou, Dangxia, Huang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031920/
https://www.ncbi.nlm.nih.gov/pubmed/36944972
http://dx.doi.org/10.1186/s13578-023-01002-w

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