Granulomatous cheilitis of Miescher: a rare entity

BACKGROUND: Granulomatous cheilitis (GC) is a rare entity of unknown etiology. It is a chronic inflammatory disorder with a predilection for young females. It is characterized by asymptomatic unrelenting swelling of lips. It is a monosymptomatic form or an incomplete variant of Melkersson-Rosenthal...

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Autores principales: Tummidi, Santosh, Nagendran, Prabhakaran, Anthony, Michael Leonard, Ramani, Rupa Jami, Shankaralingappa, Arundhathi, Gopinath, Hima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031989/
https://www.ncbi.nlm.nih.gov/pubmed/36944970
http://dx.doi.org/10.1186/s12905-023-02280-9
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author Tummidi, Santosh
Nagendran, Prabhakaran
Anthony, Michael Leonard
Ramani, Rupa Jami
Shankaralingappa, Arundhathi
Gopinath, Hima
author_facet Tummidi, Santosh
Nagendran, Prabhakaran
Anthony, Michael Leonard
Ramani, Rupa Jami
Shankaralingappa, Arundhathi
Gopinath, Hima
author_sort Tummidi, Santosh
collection PubMed
description BACKGROUND: Granulomatous cheilitis (GC) is a rare entity of unknown etiology. It is a chronic inflammatory disorder with a predilection for young females. It is characterized by asymptomatic unrelenting swelling of lips. It is a monosymptomatic form or an incomplete variant of Melkersson-Rosenthal syndrome (a triad of recurrent orofacial swelling, relapsing facial paralysis, and fissuring of the tongue). CASE PRESENTATION: We herewith report a case of a 27-year-old female, presenting with persistent upper lip swelling, for 3 months. Biopsy from the lesion revealed features of granulomatous cheilitis. CONCLUSION: GC should be considered in the differential diagnosis of unrelenting swelling in the lip. Spontaneous remission is rare, and recurrences are common. Corticosteroids used for treatment provide temporary improvement.
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spelling pubmed-100319892023-03-23 Granulomatous cheilitis of Miescher: a rare entity Tummidi, Santosh Nagendran, Prabhakaran Anthony, Michael Leonard Ramani, Rupa Jami Shankaralingappa, Arundhathi Gopinath, Hima BMC Womens Health Case Report BACKGROUND: Granulomatous cheilitis (GC) is a rare entity of unknown etiology. It is a chronic inflammatory disorder with a predilection for young females. It is characterized by asymptomatic unrelenting swelling of lips. It is a monosymptomatic form or an incomplete variant of Melkersson-Rosenthal syndrome (a triad of recurrent orofacial swelling, relapsing facial paralysis, and fissuring of the tongue). CASE PRESENTATION: We herewith report a case of a 27-year-old female, presenting with persistent upper lip swelling, for 3 months. Biopsy from the lesion revealed features of granulomatous cheilitis. CONCLUSION: GC should be considered in the differential diagnosis of unrelenting swelling in the lip. Spontaneous remission is rare, and recurrences are common. Corticosteroids used for treatment provide temporary improvement. BioMed Central 2023-03-21 /pmc/articles/PMC10031989/ /pubmed/36944970 http://dx.doi.org/10.1186/s12905-023-02280-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Tummidi, Santosh
Nagendran, Prabhakaran
Anthony, Michael Leonard
Ramani, Rupa Jami
Shankaralingappa, Arundhathi
Gopinath, Hima
Granulomatous cheilitis of Miescher: a rare entity
title Granulomatous cheilitis of Miescher: a rare entity
title_full Granulomatous cheilitis of Miescher: a rare entity
title_fullStr Granulomatous cheilitis of Miescher: a rare entity
title_full_unstemmed Granulomatous cheilitis of Miescher: a rare entity
title_short Granulomatous cheilitis of Miescher: a rare entity
title_sort granulomatous cheilitis of miescher: a rare entity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031989/
https://www.ncbi.nlm.nih.gov/pubmed/36944970
http://dx.doi.org/10.1186/s12905-023-02280-9
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