Sequential Therapy of Linezolid and Contezolid to Treat Vancomycin-Resistant Enterococcus faecium Pneumonia in a Centenarian Patient: Case Report

Enterococcus faecium (E. faecium) is one of the core components of enterococci and causes serious illnesses in the elderly and immunocompromised patients. Due to its adaptive traits and antibiotic resistance, E. faecium has evolved as a worldwide hospital-associated pathogen, especially vancomsycin-...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Pengzhi, An, Li, Zhang, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032165/
https://www.ncbi.nlm.nih.gov/pubmed/36969942
http://dx.doi.org/10.2147/IDR.S401533
_version_ 1784910741190475776
author Chen, Pengzhi
An, Li
Zhang, Zhijian
author_facet Chen, Pengzhi
An, Li
Zhang, Zhijian
author_sort Chen, Pengzhi
collection PubMed
description Enterococcus faecium (E. faecium) is one of the core components of enterococci and causes serious illnesses in the elderly and immunocompromised patients. Due to its adaptive traits and antibiotic resistance, E. faecium has evolved as a worldwide hospital-associated pathogen, especially vancomsycin-resistant Enterococcus faecium (VREfm). Pneumonia caused by VREfm is quite rare in clinical settings, and optimal treatment has not yet been determined. Here, we present a case of nosocomial VREfm pneumonia with lung cavitation following adenovirus infection, which was successfully treated with linezolid and contezolid.
format Online
Article
Text
id pubmed-10032165
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-100321652023-03-23 Sequential Therapy of Linezolid and Contezolid to Treat Vancomycin-Resistant Enterococcus faecium Pneumonia in a Centenarian Patient: Case Report Chen, Pengzhi An, Li Zhang, Zhijian Infect Drug Resist Case Report Enterococcus faecium (E. faecium) is one of the core components of enterococci and causes serious illnesses in the elderly and immunocompromised patients. Due to its adaptive traits and antibiotic resistance, E. faecium has evolved as a worldwide hospital-associated pathogen, especially vancomsycin-resistant Enterococcus faecium (VREfm). Pneumonia caused by VREfm is quite rare in clinical settings, and optimal treatment has not yet been determined. Here, we present a case of nosocomial VREfm pneumonia with lung cavitation following adenovirus infection, which was successfully treated with linezolid and contezolid. Dove 2023-03-18 /pmc/articles/PMC10032165/ /pubmed/36969942 http://dx.doi.org/10.2147/IDR.S401533 Text en © 2023 Chen et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Chen, Pengzhi
An, Li
Zhang, Zhijian
Sequential Therapy of Linezolid and Contezolid to Treat Vancomycin-Resistant Enterococcus faecium Pneumonia in a Centenarian Patient: Case Report
title Sequential Therapy of Linezolid and Contezolid to Treat Vancomycin-Resistant Enterococcus faecium Pneumonia in a Centenarian Patient: Case Report
title_full Sequential Therapy of Linezolid and Contezolid to Treat Vancomycin-Resistant Enterococcus faecium Pneumonia in a Centenarian Patient: Case Report
title_fullStr Sequential Therapy of Linezolid and Contezolid to Treat Vancomycin-Resistant Enterococcus faecium Pneumonia in a Centenarian Patient: Case Report
title_full_unstemmed Sequential Therapy of Linezolid and Contezolid to Treat Vancomycin-Resistant Enterococcus faecium Pneumonia in a Centenarian Patient: Case Report
title_short Sequential Therapy of Linezolid and Contezolid to Treat Vancomycin-Resistant Enterococcus faecium Pneumonia in a Centenarian Patient: Case Report
title_sort sequential therapy of linezolid and contezolid to treat vancomycin-resistant enterococcus faecium pneumonia in a centenarian patient: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032165/
https://www.ncbi.nlm.nih.gov/pubmed/36969942
http://dx.doi.org/10.2147/IDR.S401533
work_keys_str_mv AT chenpengzhi sequentialtherapyoflinezolidandcontezolidtotreatvancomycinresistantenterococcusfaeciumpneumoniainacentenarianpatientcasereport
AT anli sequentialtherapyoflinezolidandcontezolidtotreatvancomycinresistantenterococcusfaeciumpneumoniainacentenarianpatientcasereport
AT zhangzhijian sequentialtherapyoflinezolidandcontezolidtotreatvancomycinresistantenterococcusfaeciumpneumoniainacentenarianpatientcasereport

Ejemplares similares