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Melatonin protects human nucleus pulposus cells from pyroptosis by regulating Nrf2 via melatonin membrane receptors

AIMS: This study was performed to explore the effect of melatonin on pyroptosis in nucleus pulposus cells (NPCs) and the underlying mechanism of that effect. METHODS: This experiment included three patients diagnosed with lumbar disc herniation who failed conservative treatment. Nucleus pulposus tis...

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Detalles Bibliográficos
Autores principales:	Bai, Zhibiao, Shou, Zeyu, Hu, Kai, Yu, Jiahuan, Meng, Hongming, Chen, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The British Editorial Society of Bone & Joint Surgery 2023
Materias:	Spine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032228/ https://www.ncbi.nlm.nih.gov/pubmed/37051810 http://dx.doi.org/10.1302/2046-3758.123.BJR-2022-0199.R1

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