Single-cell and spatial transcriptomics during human organogenesis

The molecular and cellular events that occur during the onset of human organogenesis remain mysterious. We used single-cell and spatial transcriptomics to provide a global view of human embryonic cell-type specification, shedding light on developmental processes such as axial patterning, stage trans...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Research Briefing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032247/
https://www.ncbi.nlm.nih.gov/pubmed/36949166
http://dx.doi.org/10.1038/s41556-023-01113-z
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description The molecular and cellular events that occur during the onset of human organogenesis remain mysterious. We used single-cell and spatial transcriptomics to provide a global view of human embryonic cell-type specification, shedding light on developmental processes such as axial patterning, stage transition, and differences between human and mouse embryonic development.
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spelling pubmed-100322472023-03-23 Single-cell and spatial transcriptomics during human organogenesis Nat Cell Biol Research Briefing The molecular and cellular events that occur during the onset of human organogenesis remain mysterious. We used single-cell and spatial transcriptomics to provide a global view of human embryonic cell-type specification, shedding light on developmental processes such as axial patterning, stage transition, and differences between human and mouse embryonic development. Nature Publishing Group UK 2023-03-22 2023 /pmc/articles/PMC10032247/ /pubmed/36949166 http://dx.doi.org/10.1038/s41556-023-01113-z Text en © Springer Nature Limited 2023 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Research Briefing
Single-cell and spatial transcriptomics during human organogenesis
title Single-cell and spatial transcriptomics during human organogenesis
title_full Single-cell and spatial transcriptomics during human organogenesis
title_fullStr Single-cell and spatial transcriptomics during human organogenesis
title_full_unstemmed Single-cell and spatial transcriptomics during human organogenesis
title_short Single-cell and spatial transcriptomics during human organogenesis
title_sort single-cell and spatial transcriptomics during human organogenesis
topic Research Briefing
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032247/
https://www.ncbi.nlm.nih.gov/pubmed/36949166
http://dx.doi.org/10.1038/s41556-023-01113-z

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