Hyperlipidaemia elicits an atypical, T helper 1–like CD4(+) T-cell response: a key role for very low-density lipoprotein

AIMS: Hyperlipidemia and T cell driven inflammation are important drivers of atherosclerosis, the main underlying cause of cardiovascular disease. Here, we detailed the effects of hyperlipidemia on T cells. METHODS AND RESULTS: In vitro, exposure of human and murine CD4+ T cells to very low-density...

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Detalles Bibliográficos
Autores principales: van Os, Bram W, Vos, Winnie G, Bosmans, Laura A, van Tiel, Claudia M, Lith, Sanne C, den Toom, Myrthe S, Beckers, Linda, Levels, Johannes H M, van Wouw, Suzanne A E, Zelcer, Noam, Zaal, Esther A, Berkers, Celia R, van der Lest, Chris H A, Helms, J Bernd, Weber, Christian, Atzler, Dorothee, de Winther, Menno P J, Baardman, Jeroen, Lutgens, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032356/
https://www.ncbi.nlm.nih.gov/pubmed/36969380
http://dx.doi.org/10.1093/ehjopen/oead013

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