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The impact of SGLT2 inhibitors on αKlotho in renal MDCK and HK-2 cells
αKlotho is a transmembrane protein predominantly expressed in the kidney serving as a co-receptor for phosphate homeostasis-regulating hormone FGF23 and has an extracellular domain that can be cleaved off and is a hormone. αKlotho deficiency results in accelerated aging and early onset of aging-asso...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032406/ https://www.ncbi.nlm.nih.gov/pubmed/36967770 http://dx.doi.org/10.3389/fendo.2023.1069715 |