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MAdCAM-1 costimulation in the presence of retinoic acid and TGF-β promotes HIV infection and differentiation of CD4(+) T cells into CCR5(+) T(RM)-like cells
CD4(+) tissue resident memory T cells (T(RM)s) are implicated in the formation of persistent HIV reservoirs that are established during the very early stages of infection. The tissue-specific factors that direct T cells to establish tissue residency are not well defined, nor are the factors that est...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032498/ https://www.ncbi.nlm.nih.gov/pubmed/36897929 http://dx.doi.org/10.1371/journal.ppat.1011209 |