MAdCAM-1 costimulation in the presence of retinoic acid and TGF-β promotes HIV infection and differentiation of CD4(+) T cells into CCR5(+) T(RM)-like cells

CD4(+) tissue resident memory T cells (T(RM)s) are implicated in the formation of persistent HIV reservoirs that are established during the very early stages of infection. The tissue-specific factors that direct T cells to establish tissue residency are not well defined, nor are the factors that est...

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Detalles Bibliográficos
Autores principales: Vimonpatranon, Sinmanus, Goes, Livia R., Chan, Amanda, Licavoli, Isabella, McMurry, Jordan, Wertz, Samuel R., Arakelyan, Anush, Huang, Dawei, Jiang, Andrew, Huang, Cindy, Zhou, Joyce, Yolitz, Jason, Girard, Alexandre, Van Ryk, Donald, Wei, Danlan, Hwang, Il Young, Martens, Craig, Kanakabandi, Kishore, Virtaneva, Kimmo, Ricklefs, Stacy, Darwitz, Benjamin P., Soares, Marcelo A., Pattanapanyasat, Kovit, Fauci, Anthony S., Arthos, James, Cicala, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032498/
https://www.ncbi.nlm.nih.gov/pubmed/36897929
http://dx.doi.org/10.1371/journal.ppat.1011209

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