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Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection

The immunological surveillance factors controlling vulnerability of the female reproductive tract (FRT) to sexually transmitted viral infections are not well understood. Interferon-epsilon (IFNɛ) is a distinct, immunoregulatory type-I IFN that is constitutively expressed by FRT epithelium and is not...

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Detalles Bibliográficos
Autores principales: Coldbeck-Shackley, Rosa C., Romeo, Ornella, Rosli, Sarah, Gearing, Linden J., Gould, Jodee A., Lim, San S., Van der Hoek, Kylie H., Eyre, Nicholas S., Shue, Byron, Robertson, Sarah A., Best, Sonja M., Tate, Michelle D., Hertzog, Paul J., Beard, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032502/
https://www.ncbi.nlm.nih.gov/pubmed/36897927
http://dx.doi.org/10.1371/journal.ppat.1010843