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Humanized MISTRG as a preclinical in vivo model to study human neutrophil-mediated immune processes

INTRODUCTION: MISTRG mice have been genetically modified to allow development of a human myeloid compartment from engrafted human CD34+ haemopoietic stem cells, making them particularly suited to study the human innate immune system in vivo. Here, we characterized the human neutrophil population in...

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Detalles Bibliográficos
Autores principales:	Martinez-Sanz, Paula, Laurent, Adrien R. G., Slot, Edith, Hoogenboezem, Mark, Bąbała, Nikolina, van Bruggen, Robin, Rongvaux, Anthony, Flavell, Richard A., Tytgat, Godelieve A. M., Franke, Katka, Matlung, Hanke L., Kuijpers, Taco W., Amsen, Derk, Karrich, Julien J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032520/ https://www.ncbi.nlm.nih.gov/pubmed/36969261 http://dx.doi.org/10.3389/fimmu.2023.1105103

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