An innate pathogen sensing strategy involving ubiquitination of bacterial surface proteins

Sensing of pathogens by ubiquitination is a critical arm of cellular immunity. However, universal ubiquitination targets on microbes remain unidentified. Here, using in vitro, ex vivo, and in vivo studies, we identify the first protein-based ubiquitination substrates on phylogenetically diverse bact...

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Detalles Bibliográficos
Autores principales: Apte, Shruti, Bhutda, Smita, Ghosh, Sourav, Sharma, Kuldeep, Barton, Thomas E., Dibyachintan, Soham, Sahay, Osheen, Roy, Suvapriya, Sinha, Akash Raj, Adicherla, Harikrishna, Rakshit, Jyotirmoy, Tang, Shiying, Datey, Akshay, Santra, Shweta, Joseph, Jincy, Sasidharan, Sreeja, Hammerschmidt, Sven, Chakravortty, Dipshikha, Oggioni, Marco R., Santra, Manas Kumar, Neill, Daniel R., Banerjee, Anirban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032600/
https://www.ncbi.nlm.nih.gov/pubmed/36947610
http://dx.doi.org/10.1126/sciadv.ade1851

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