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O(2) variant chip to simulate site-specific skeletogenesis from hypoxic bone marrow

The stemness of bone marrow mesenchymal stem cells (BMSCs) is maintained by hypoxia. The oxygen level increases from vessel-free cartilage to hypoxic bone marrow and, furthermore, to vascularized bone, which might direct the chondrogenesis to osteogenesis and regenerate the skeletal system. Hence, o...

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Detalles Bibliográficos
Autores principales: Kim, Hye-Seon, Ha, Hyun-Su, Kim, Dae-Hyun, Son, Deok Hyeon, Baek, Sewoom, Park, Jeongeun, Lee, Chan Hee, Park, Suji, Yoon, Hyo-Jin, Yu, Seung Eun, Kang, Jeon Il, Park, Kyung Min, Shin, Young Min, Lee, Jung Bok, Sung, Hak-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032601/
https://www.ncbi.nlm.nih.gov/pubmed/36947623
http://dx.doi.org/10.1126/sciadv.add4210