Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding

Endothelial cells (ECs) grant access of disseminated cancer cells to distant organs. However, the molecular players regulating the activation of quiescent ECs at the premetastatic niche (PMN) remain elusive. Here, we find that ECs at the PMN coexpress tumor necrosis factor–related apoptosis-inducing...

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Detalles Bibliográficos
Autores principales: Riera-Domingo, Carla, Leite-Gomes, Eduarda, Charatsidou, Iris, Zhao, Peihua, Carrá, Giovanna, Cappellesso, Federica, Mourao, Larissa, De Schepper, Maxim, Liu, Dana, Serneels, Jens, Alameh, Mohamad-Gabriel, Shuvaev, Vladimir V., Geukens, Tatjana, Isnaldi, Edoardo, Prenen, Hans, Weissman, Drew, Muzykantov, Vladimir R., Soenen, Stefaan, Desmedt, Christine, Scheele, Colinda L. G. J., Sablina, Anna, Di Matteo, Mario, Martín-Pérez, Rosa, Mazzone, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032608/
https://www.ncbi.nlm.nih.gov/pubmed/36947620
http://dx.doi.org/10.1126/sciadv.add5028

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