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Continuity of CVD treatment during the COVID-19 pandemic: evidence from East Java, Indonesia

BACKGROUND: In Indonesia, the world's fourth most populous country, cardiovascular diseases (CVDs) are a leading cause of death and disability. Government efforts to reduce the burden of CVD include a community-based prevention and early detection programme, and the provision of medicines to pr...

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Autores principales: Dewi, Aksari, Pisani, Elizabeth, Ihsan, Bachtiar Rifai Pratita, Hariadini, Ayuk Lawuningtyas, Patel, Anushka, Palagyi, Anna, Praveen, Devarsetty, Sujarwoto, Lyrawati, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032625/
https://www.ncbi.nlm.nih.gov/pubmed/36949533
http://dx.doi.org/10.1186/s40545-022-00509-w
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author Dewi, Aksari
Pisani, Elizabeth
Ihsan, Bachtiar Rifai Pratita
Hariadini, Ayuk Lawuningtyas
Patel, Anushka
Palagyi, Anna
Praveen, Devarsetty
Sujarwoto
Lyrawati, Diana
author_facet Dewi, Aksari
Pisani, Elizabeth
Ihsan, Bachtiar Rifai Pratita
Hariadini, Ayuk Lawuningtyas
Patel, Anushka
Palagyi, Anna
Praveen, Devarsetty
Sujarwoto
Lyrawati, Diana
author_sort Dewi, Aksari
collection PubMed
description BACKGROUND: In Indonesia, the world's fourth most populous country, cardiovascular diseases (CVDs) are a leading cause of death and disability. Government efforts to reduce the burden of CVD include a community-based prevention and early detection programme, and the provision of medicines to prevent cardiovascular events. Disruptions to medicine supply chains, service provision, and movement during the COVID-19 pandemic potentially threatened the continuity of these efforts. We investigated the distribution and dispensing of common CVD medicines in Malang district, East Java, before the pandemic and early in its course. METHODS: From January to October 2020, we collected monthly data on stock levels, sales or dispensing volumes, and price for five common CVD medicines (amlodipine, captopril, furosemide, glibenclamide and simvastatin), from a public and a private distributor, and from public health facilities (n = 4) and private pharmacies (n = 2). We further complied monthly data on patient numbers in two primary health centres. We tracked changes in stocks held and volumes dispensed by medicine type and sector, comparing the three months before the local COVID-19 response was mobilised with the subsequent seven months. We conducted interviews with pharmacists (n = 12), community health workers (n = 2) and a supply chain logistics manager to investigate the reasons for observed changes, and to learn details of any impacts or mitigation measures. RESULTS: The pandemic affected demand more than supply, causing medicine stocks to rise. Restricted service provision, lock-down measures and fear of infection contributed to a sharp drop in patient numbers and dispensing volumes in the public sector. Meanwhile private sector sales, especially of lower-priced CVD medicines, rose. Community health workers attributed some poor health outcomes to interruption in regular patient check-ups; this interruption was aggravated by formal mitigation policies. CONCLUSIONS: Fears that COVID-19 would interrupt medicine availability were unfounded in East Java. Public sector patients may have compensated for reduced service access by switching to private pharmacies. Mitigation policies that ignored administrative procedures were not effective. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40545-022-00509-w.
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spelling pubmed-100326252023-03-23 Continuity of CVD treatment during the COVID-19 pandemic: evidence from East Java, Indonesia Dewi, Aksari Pisani, Elizabeth Ihsan, Bachtiar Rifai Pratita Hariadini, Ayuk Lawuningtyas Patel, Anushka Palagyi, Anna Praveen, Devarsetty Sujarwoto Lyrawati, Diana J Pharm Policy Pract Research BACKGROUND: In Indonesia, the world's fourth most populous country, cardiovascular diseases (CVDs) are a leading cause of death and disability. Government efforts to reduce the burden of CVD include a community-based prevention and early detection programme, and the provision of medicines to prevent cardiovascular events. Disruptions to medicine supply chains, service provision, and movement during the COVID-19 pandemic potentially threatened the continuity of these efforts. We investigated the distribution and dispensing of common CVD medicines in Malang district, East Java, before the pandemic and early in its course. METHODS: From January to October 2020, we collected monthly data on stock levels, sales or dispensing volumes, and price for five common CVD medicines (amlodipine, captopril, furosemide, glibenclamide and simvastatin), from a public and a private distributor, and from public health facilities (n = 4) and private pharmacies (n = 2). We further complied monthly data on patient numbers in two primary health centres. We tracked changes in stocks held and volumes dispensed by medicine type and sector, comparing the three months before the local COVID-19 response was mobilised with the subsequent seven months. We conducted interviews with pharmacists (n = 12), community health workers (n = 2) and a supply chain logistics manager to investigate the reasons for observed changes, and to learn details of any impacts or mitigation measures. RESULTS: The pandemic affected demand more than supply, causing medicine stocks to rise. Restricted service provision, lock-down measures and fear of infection contributed to a sharp drop in patient numbers and dispensing volumes in the public sector. Meanwhile private sector sales, especially of lower-priced CVD medicines, rose. Community health workers attributed some poor health outcomes to interruption in regular patient check-ups; this interruption was aggravated by formal mitigation policies. CONCLUSIONS: Fears that COVID-19 would interrupt medicine availability were unfounded in East Java. Public sector patients may have compensated for reduced service access by switching to private pharmacies. Mitigation policies that ignored administrative procedures were not effective. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40545-022-00509-w. BioMed Central 2023-03-22 /pmc/articles/PMC10032625/ /pubmed/36949533 http://dx.doi.org/10.1186/s40545-022-00509-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Dewi, Aksari
Pisani, Elizabeth
Ihsan, Bachtiar Rifai Pratita
Hariadini, Ayuk Lawuningtyas
Patel, Anushka
Palagyi, Anna
Praveen, Devarsetty
Sujarwoto
Lyrawati, Diana
Continuity of CVD treatment during the COVID-19 pandemic: evidence from East Java, Indonesia
title Continuity of CVD treatment during the COVID-19 pandemic: evidence from East Java, Indonesia
title_full Continuity of CVD treatment during the COVID-19 pandemic: evidence from East Java, Indonesia
title_fullStr Continuity of CVD treatment during the COVID-19 pandemic: evidence from East Java, Indonesia
title_full_unstemmed Continuity of CVD treatment during the COVID-19 pandemic: evidence from East Java, Indonesia
title_short Continuity of CVD treatment during the COVID-19 pandemic: evidence from East Java, Indonesia
title_sort continuity of cvd treatment during the covid-19 pandemic: evidence from east java, indonesia
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032625/
https://www.ncbi.nlm.nih.gov/pubmed/36949533
http://dx.doi.org/10.1186/s40545-022-00509-w
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