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Development of HPLC-CAD method for simultaneous quantification of nine related substances in ursodeoxycholic acid and identification of two unknown impurities by HPLC-Q-TOF-MS

Ursodeoxycholic acid has gained increasing attention due to its recent discovery of the preventive effect on SARS-CoV-2 infection. Ursodeoxycholic acid has been included in various pharmacopoeias as an old drug, and the latest European Pharmacopoeia lists nine potential related substances (impuritie...

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Detalles Bibliográficos
Autores principales:	Huang, Yiwen, Lu, Hui, Li, Zhong, Zeng, Yuan, Xu, Qi, Wu, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033147/ https://www.ncbi.nlm.nih.gov/pubmed/36966621 http://dx.doi.org/10.1016/j.jpba.2023.115357

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