Inflammatory Cell Infiltration Into Islets Without PD-L1 Expression Is Associated With the Development of Immune Checkpoint Inhibitor–Related Type 1 Diabetes in Genetically Susceptible Patients

Immune checkpoint inhibitors (ICIs) could cause type 1 diabetes (T1D). However, the underlying mechanism remains unclear. We immunohistochemically analyzed pancreatic specimens from three individuals with ICI-related T1D, and their histopathological data were compared those from three patients who h...

Descripción completa

Detalles Bibliográficos
Autores principales: Kawata, Satoshi, Kozawa, Junji, Yoneda, Sho, Fujita, Yukari, Kashiwagi-Takayama, Risa, Kimura, Takekazu, Hosokawa, Yoshiya, Baden, Megu Y., Uno, Sae, Uenaka, Rikako, Namai, Kazuyuki, Koh, Yoko, Tomimaru, Yoshito, Hirata, Haruhiko, Uemura, Motohide, Nojima, Satoshi, Morii, Eiichi, Eguchi, Hidetoshi, Imagawa, Akihisa, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033247/
https://www.ncbi.nlm.nih.gov/pubmed/36657987
http://dx.doi.org/10.2337/db22-0557

Ejemplares similares

Ejemplares similares