Lipidomic profiling of rat hepatic stellate cells during activation reveals a two-stage process accompanied by increased levels of lysosomal lipids

Hepatic stellate cells (HSCs) are liver-resident cells best known for their role in vitamin A storage under physiological conditions. Upon liver injury, HSCs activate into myofibroblast-like cells, a key process in the onset of liver fibrosis. Lipids play an important role during HSC activation. Her...

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Detalles Bibliográficos
Autores principales: Molenaar, Martijn R., Haaker, Maya W., Vaandrager, A. Bas, Houweling, Martin, Helms, J. Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033282/
https://www.ncbi.nlm.nih.gov/pubmed/36803964
http://dx.doi.org/10.1016/j.jbc.2023.103042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033282/
https://www.ncbi.nlm.nih.gov/pubmed/36803964
http://dx.doi.org/10.1016/j.jbc.2023.103042

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