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Research Progress of Fever with Thrombocytopenia Syndrome
Severe fever with thrombocytopenia syndrome (SFTS) is a new infectious disease first discovered in Ta-pieh Mountains in central China in 2009. It is caused by a novel bunyavirus infection (SFTSV). Since the first discovery of SFTSV, there have been case reports and epidemiological studies on SFTS in...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033304/ https://www.ncbi.nlm.nih.gov/pubmed/37360310 http://dx.doi.org/10.1007/s44231-023-00035-6 |
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author | Luo, Ning Li, Mengdie Xu, Ming Shi, Chuanchuan Shi, Xinge Ni, Rong Chen, Yu Zheng, Liang Tu, Yuling Hu, Dan Yu, Chunlin Li, Qingying Lu, Yibin |
author_facet | Luo, Ning Li, Mengdie Xu, Ming Shi, Chuanchuan Shi, Xinge Ni, Rong Chen, Yu Zheng, Liang Tu, Yuling Hu, Dan Yu, Chunlin Li, Qingying Lu, Yibin |
author_sort | Luo, Ning |
collection | PubMed |
description | Severe fever with thrombocytopenia syndrome (SFTS) is a new infectious disease first discovered in Ta-pieh Mountains in central China in 2009. It is caused by a novel bunyavirus infection (SFTSV). Since the first discovery of SFTSV, there have been case reports and epidemiological studies on SFTS in several East Asian countries, such as South Korea, Japan, Vietnam and so on. With the rising incidence of SFTS and the rapid spread of the novel bunyavirus around the world, it is clear that the virus has a pandemic potential and may pose a threat to global public health in the future. Early studies have suggested that ticks are an important medium for the transmission of SFTSV to humans; in recent years, it has been reported that there is also human-to-human transmission. In endemic areas, potential hosts include a variety of livestock and wildlife. When people are infected with SFTV, the main clinical manifestations are high fever, thrombocytopenia, leukocytopenia, gastrointestinal symptoms, liver and kidney function damage, and even MODS, with a mortality rate of about 10–30%. This article reviews the latest progress of novel bunyavirus, including virus transmission vector, virus genotypic diversity and epidemiology, pathogenesis, clinical manifestation and treatment. |
format | Online Article Text |
id | pubmed-10033304 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-100333042023-03-23 Research Progress of Fever with Thrombocytopenia Syndrome Luo, Ning Li, Mengdie Xu, Ming Shi, Chuanchuan Shi, Xinge Ni, Rong Chen, Yu Zheng, Liang Tu, Yuling Hu, Dan Yu, Chunlin Li, Qingying Lu, Yibin Intensive Care Res Review Article Severe fever with thrombocytopenia syndrome (SFTS) is a new infectious disease first discovered in Ta-pieh Mountains in central China in 2009. It is caused by a novel bunyavirus infection (SFTSV). Since the first discovery of SFTSV, there have been case reports and epidemiological studies on SFTS in several East Asian countries, such as South Korea, Japan, Vietnam and so on. With the rising incidence of SFTS and the rapid spread of the novel bunyavirus around the world, it is clear that the virus has a pandemic potential and may pose a threat to global public health in the future. Early studies have suggested that ticks are an important medium for the transmission of SFTSV to humans; in recent years, it has been reported that there is also human-to-human transmission. In endemic areas, potential hosts include a variety of livestock and wildlife. When people are infected with SFTV, the main clinical manifestations are high fever, thrombocytopenia, leukocytopenia, gastrointestinal symptoms, liver and kidney function damage, and even MODS, with a mortality rate of about 10–30%. This article reviews the latest progress of novel bunyavirus, including virus transmission vector, virus genotypic diversity and epidemiology, pathogenesis, clinical manifestation and treatment. Springer Netherlands 2023-03-23 /pmc/articles/PMC10033304/ /pubmed/37360310 http://dx.doi.org/10.1007/s44231-023-00035-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Review Article Luo, Ning Li, Mengdie Xu, Ming Shi, Chuanchuan Shi, Xinge Ni, Rong Chen, Yu Zheng, Liang Tu, Yuling Hu, Dan Yu, Chunlin Li, Qingying Lu, Yibin Research Progress of Fever with Thrombocytopenia Syndrome |
title | Research Progress of Fever with Thrombocytopenia Syndrome |
title_full | Research Progress of Fever with Thrombocytopenia Syndrome |
title_fullStr | Research Progress of Fever with Thrombocytopenia Syndrome |
title_full_unstemmed | Research Progress of Fever with Thrombocytopenia Syndrome |
title_short | Research Progress of Fever with Thrombocytopenia Syndrome |
title_sort | research progress of fever with thrombocytopenia syndrome |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033304/ https://www.ncbi.nlm.nih.gov/pubmed/37360310 http://dx.doi.org/10.1007/s44231-023-00035-6 |
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