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Expression of GnT-III decreases chemoresistance via negatively regulating P-glycoprotein expression: Involvement of the TNFR2-NF-κB signaling pathway

The phenomenon of multidrug resistance (MDR) is called chemoresistance with respect to the treatment of cancer, and it continues to be a major challenge. The role of N-glycosylation in chemoresistance, however, remains poorly understood. Here, we established a traditional model for adriamycin resist...

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Detalles Bibliográficos
Autores principales: Song, Wanli, Liang, Caixia, Sun, Yuhan, Morii, Sayaka, Yomogida, Shin, Isaji, Tomoya, Fukuda, Tomohiko, Hang, Qinglei, Hara, Akiyoshi, Nakano, Miyako, Gu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033316/
https://www.ncbi.nlm.nih.gov/pubmed/36813234
http://dx.doi.org/10.1016/j.jbc.2023.103051