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Electrical signals in the ER are cell type and stimulus specific with extreme spatial compartmentalization in neurons
The endoplasmic reticulum (ER) is a tortuous organelle that spans throughout a cell with a continuous membrane containing ion channels, pumps, and transporters. It is unclear if stimuli that gate ER ion channels trigger substantial membrane potential fluctuations and if those fluctuations spread bey...
Autores principales: | Campbell, Evan P., Abushawish, Ahmed A., Valdez, Lauren A., Bell, Miriam K., Haryono, Melita, Rangamani, Padmini, Bloodgood, Brenda L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033362/ https://www.ncbi.nlm.nih.gov/pubmed/36640310 http://dx.doi.org/10.1016/j.celrep.2022.111943 |
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