In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

Despite scientific evidence originating from two patients published to date that CCR5Δ32/Δ32 hematopoietic stem cell transplantation (HSCT) can cure human immunodeficiency virus type 1 (HIV-1), the knowledge of immunological and virological correlates of cure is limited. Here we characterize a case...

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Detalles Bibliográficos
Autores principales: Jensen, Björn-Erik Ole, Knops, Elena, Cords, Leon, Lübke, Nadine, Salgado, Maria, Busman-Sahay, Kathleen, Estes, Jacob D., Huyveneers, Laura E. P., Perdomo-Celis, Federico, Wittner, Melanie, Gálvez, Cristina, Mummert, Christiane, Passaes, Caroline, Eberhard, Johanna M., Münk, Carsten, Hauber, Ilona, Hauber, Joachim, Heger, Eva, De Clercq, Jozefien, Vandekerckhove, Linos, Bergmann, Silke, Dunay, Gábor A., Klein, Florian, Häussinger, Dieter, Fischer, Johannes C., Nachtkamp, Kathrin, Timm, Joerg, Kaiser, Rolf, Harrer, Thomas, Luedde, Tom, Nijhuis, Monique, Sáez-Cirión, Asier, Schulze zur Wiesch, Julian, Wensing, Annemarie M. J., Martinez-Picado, Javier, Kobbe, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033413/
https://www.ncbi.nlm.nih.gov/pubmed/36807684
http://dx.doi.org/10.1038/s41591-023-02213-x

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