Multi-modal efficacy of a chimeric vesiculovirus expressing the Morreton glycoprotein in sarcoma

Vesiculoviruses are attractive oncolytic virus platforms due to their rapid replication, appreciable transgene capacity, broad tropism, limited preexisting immunity, and tumor selectivity through type I interferon response defects in malignant cells. We developed a synthetic chimeric virus (VMG) exp...

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Detalles Bibliográficos
Autores principales: Watters, Chelsae R., Barro, Oumar, Elliott, Natalie M., Zhou, Yumei, Gabere, Musa, Raupach, Elizabeth, Baker, Alexander T., Barrett, Michael T., Buetow, Kenneth H., Jacobs, Bertram, Seetharam, Mahesh, Borad, Mitesh J., Nagalo, Bolni Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033453/
https://www.ncbi.nlm.nih.gov/pubmed/36969560
http://dx.doi.org/10.1016/j.omto.2023.02.009

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