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A defect in mitochondrial protein translation influences mitonuclear communication in the heart

The regulation of the informational flow from the mitochondria to the nucleus (mitonuclear communication) is not fully characterized in the heart. We have determined that mitochondrial ribosomal protein S5 (MRPS5/uS5m) can regulate cardiac function and key pathways to coordinate this process during...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Liang, Tian, Lu, Yao Wei, Fu, Xuyang, Dong, Xiaoxuan, Pu, Linbin, Hong, Tingting, Zhou, Yuxia, Zhang, Yu, Liu, Ning, Zhang, Feng, Liu, Jianming, Malizia, Andrea P., Yu, Hong, Zhu, Wei, Cowan, Douglas B., Chen, Hong, Hu, Xinyang, Mably, John D., Wang, Jian’an, Wang, Da-Zhi, Chen, Jinghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033703/
https://www.ncbi.nlm.nih.gov/pubmed/36949106
http://dx.doi.org/10.1038/s41467-023-37291-5