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New AAV tools fail to detect Neurod1-mediated neuronal conversion of Müller glia and astrocytes in vivo
BACKGROUND: Reprogramming resident glial cells to convert them into neurons in vivo represents a potential therapeutic strategy that could replenish lost neurons, repair damaged neural circuits, and restore function. AAV (adeno-associated virus)-based expression systems are powerful tools for in viv...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033723/ https://www.ncbi.nlm.nih.gov/pubmed/36947961 http://dx.doi.org/10.1016/j.ebiom.2023.104531 |