Blocking dPerk in the intestine suppresses neurodegeneration in a Drosophila model of Parkinson’s disease

Parkinson’s disease (PD) is characterised by selective death of dopaminergic (DA) neurons in the midbrain and motor function impairment. Gastrointestinal issues often precede motor deficits in PD, indicating that the gut-brain axis is involved in the pathogenesis of this disease. The features of PD...

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Detalles Bibliográficos
Autores principales: Popovic, Rebeka, Mukherjee, Amrita, Leal, Nuno Santos, Morris, Lydia, Yu, Yizhou, Loh, Samantha H. Y., Miguel Martins, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033872/
https://www.ncbi.nlm.nih.gov/pubmed/36949073
http://dx.doi.org/10.1038/s41419-023-05729-9

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