IGFBP5 is an ROR1 ligand promoting glioblastoma invasion via ROR1/HER2-CREB signaling axis

Diffuse infiltration is the main reason for therapeutic resistance and recurrence in glioblastoma (GBM). However, potential targeted therapies for GBM stem-like cell (GSC) which is responsible for GBM invasion are limited. Herein, we report Insulin-like Growth Factor-Binding Protein 5 (IGFBP5) is a...

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Detalles Bibliográficos
Autores principales: Lin, Weiwei, Niu, Rui, Park, Seong-Min, Zou, Yan, Kim, Sung Soo, Xia, Xue, Xing, Songge, Yang, Qingshan, Sun, Xinhong, Yuan, Zheng, Zhou, Shuchang, Zhang, Dongya, Kwon, Hyung Joon, Park, Saewhan, Il Kim, Chan, Koo, Harim, Liu, Yang, Wu, Haigang, Zheng, Meng, Yoo, Heon, Shi, Bingyang, Park, Jong Bae, Yin, Jinlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033905/
https://www.ncbi.nlm.nih.gov/pubmed/36949068
http://dx.doi.org/10.1038/s41467-023-37306-1

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